a novel rationally designed lanthanoid chelating tag

  • a novel rationally designed lanthanoid chelating tag

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Stable and rigid DTPA-like paramagnetic tags suitable for a novel rationally designed lanthanoid chelating tag

A paramagnetic tag generally contains a metal chelating moiety and a reactive group for protein modification. Herein we report two new DTPA-like tags, 4PS-PyDTTA and 4PS-6M-PyDTTA that can be site-specifically attached to a protein with a stable thioether bond.Rational design of lanthanide binding peptides - ScienceDirectJun 01, 2013 · A lanthanide-finger was recently designed by replacing the cysteine and histidine residues involved in the metal coordination of a compact zinc finger (Cys2 His 2) Pyridine-2-Thiol - an overview | ScienceDirect TopicsIn 2006, two novel EDTA chelators were reported by Haberz et al. that lead to linearly independent anisotropy parameters when compared to previously synthesized EDTA-tags. 127 Interestingly, the LCTs were applied for the solution structure refinement of trigger factor and the authors demonstrated that the affinity of the newly synthesized LCTs for lanthanoids is higher than the one of the native metal

Publications | Research Group Häussinger

"A novel, rationally designed lanthanoid chelating tag delivers large paramagnetic structural restraints for biomolecular NMR." D. Joss, F. Winter, D. Häussinger, Chem. Commun., 2020, 56, 12861-12864. "Divergent Synthesis of Bioactive Dithiodiketopiperazine Natural Products Based on a Double C(sp 3)-H Activation Strategy."Prof. Dr. Daniel Häussinger | Research Group HäussingerSelected Publications "A novel, rationally designed lanthanoid chelating tag delivers large paramagnetic structural restraints for biomolecular NMR." D. Joss, F. Winter, D. Häussinger, Chemical Communications, 2020, 56, 12861-12864.NMR Structure Determination of ProteinLigand Complexes Jan 10, 2007 · A novel, rationally designed lanthanoid chelating tag delivers large paramagnetic structural restraints for biomolecular NMR. Chemical Communications 2020, 56 (84), 12861-12864. https://doi.org/10.1039/D0CC04337K Michele Invernici, Inês B. Trindade, Francesca Cantini, Ricardo O. Louro, Mario Piccioli.

Medscape | Chem Commun (Camb) - Publication Information

A novel, rationally designed lanthanoid chelating tag delivers large paramagnetic structural restraints for biomolecular NMR. October 28, 2020 [ MEDLINE Abstract ]Matthew Chambers | LSU ChemistryA key component controlling the manner in which the surfaces evolve is the dissolution equilibria at the solid/liquid interface. The Chambers Group will seek to perturb these underlying dissolution equilibria though the use of rationally designed inert chelating agents in solution.Some results are removed in response to a notice of local law requirement. For more information, please see here.Ligand-driven conformational changes of MurD visualized by a novel rationally designed lanthanoid chelating tagNov 19, 2015 · A novel, rationally designed lanthanoid chelating tag delivers large paramagnetic structural restraints for biomolecular NMR Daniel Joss, Florine Winter & Daniel HäussingerCited by: 18Publish Year: 2015Author: Tomohide Saio, Tomohide Saio, Kenji Ogura, Hiroyuki Kumeta, Yoshihiro Kobashigawa, Kazumi Shimizu, M a novel rationally designed lanthanoid chelating tag

Lanthanoid tagging via an unnatural amino acid for protein a novel rationally designed lanthanoid chelating tag

Lanthanoid pseudo-contact shift (PCS) provides long-range structural information between a paramagnetic tag and protein nuclei. However, for proteins with native cysteines, site-specific attachment may only utilize functional groups orthogonal to sulfhydryl chemistry. Here we report two lanthanoid probes, DTTA-C3-yne and DTTA-C4-yne, which can be conjugated to an unnatural amino acid pAzF In-Cell Protein Structures from 2D NMR Experiments | The a novel rationally designed lanthanoid chelating tagA novel, rationally designed lanthanoid chelating tag delivers large paramagnetic structural restraints for biomolecular NMR. Chemical Communications 2020, 56 (84) , 12861-12864. https://doi.org/10.1039/D0CC04337K; Thomas Müntener, Raphael Böhm, Kenneth Atz, Daniel Häussinger, Sebastian Hiller.Fixed-Component Lanthanide-Hybrid-Fabricated Full-Color a novel rationally designed lanthanoid chelating tagHerein, full-color photoluminescent films have been designed and fabricated facilely with a fixed-component Ln-based (Ln=Tb and Eu) polymer hybrid doped with a proton-sensitive amide-type a novel rationally designed lanthanoid chelating tag

Ethylenediaminetetraacetic Acid - an overview a novel rationally designed lanthanoid chelating tag

T.J. Keane, a novel rationally designed lanthanoid chelating tag S.F. Badylak, in Characterisation and Design of Tissue Scaffolds, 2016. Chelating agents. Ethylenediaminetetraacetic acid (EDTA) and ethylene glycol tetraacetic acid (EGTA) are commonly used chelating agents that bind divalent metal cations at cell adhesion sites of the ECM. This sequestering causes cell dissociation from the ECM. EDTA and EGTA can be used with trypsin (Xu et a novel rationally designed lanthanoid chelating tagDipicolinic Acid - an overview | ScienceDirect TopicsView chapter Purchase book. a novel rationally designed lanthanoid chelating tag NTA- and Pyridine-Based Lanthanoid Chelating Tags. a novel rationally designed lanthanoid chelating tag Jia et al. extended the repertoire of dipicolinic acid derived LCTs by the design and synthesis of 4MDPA that includes a short linker in the 4-position of the pyridine scaffold. 131 While the tag offers quantitative tagging yields, the obtained anisotropy a novel rationally designed lanthanoid chelating tagDesign, Synthesis, and Evaluation of a Lanthanide a novel rationally designed lanthanoid chelating tagThe lanthanide chelating tag studied in this work offer insights into the solution structure of proteins by inducing strong pseudocontact shifts, show different tensor properties compared to its a novel rationally designed lanthanoid chelating tag

Design, Synthesis, and Evaluation of a Lanthanide a novel rationally designed lanthanoid chelating tag

A novel, rationally designed lanthanoid chelating tag delivers large paramagnetic structural restraints for biomolecular NMR. Chemical Communications 2020, 56 (84) , 12861-12864.Cited by: 170Publish Year: 2008Author: Peter H. J. Keizers, Athanasios Saragliadis, Yoshitaka Hiruma, Mark Overhand, Marcellus UbbinkDaniel Joss | Research Group HäussingerPublications. "A novel, rationally designed lanthanoid chelating tag delivers large paramagnetic structural restraints for biomolecular NMR." D. Joss, F. Winter, D. Häussinger, Chemical Communications, 2020, 56, 12861-12864. "Application of paramagnetic lanthanoid chelating tags in NMR spectroscopy and their use for the localization of ligands within biomacromolecules."Daniel Häussinger's research works | University of Basel a novel rationally designed lanthanoid chelating tagA novel, rationally designed lanthanoid chelating tag delivers large paramagnetic structural restraints for biomolecular NMR

The boiler steel is not only required to have good corrosion resistance at low temperature, but also required to have good oxidation resistance at high temperature for components working at high temperature. Especially for the components of superheater and reheater, when they a novel rationally designed lanthanoid chelating tag work at high temperature, they are required not easy to be oxidized and peeled. Generally, the development speed of oxidation depth at working temperature is required to be less than 0.1mm\/year. The addition of chromium, nickel, aluminum and silicon can improve the oxidation resistance of steel.

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